EPO Signaling Pathway
| PAG Title | EPO Signaling Pathway |
| PAG ID | WIG000315 |
| Type | P |
| Source Link |  MSigDB |
| Publication Reference | NA |
| PAG Description | Erythropoietin functions to increase the number of red blood cells. Thus, it has found utility as a drug for those needing to replenish erythrocytes for a number of reasons. The signaling mechanism includes multimerization of the receptor upon ligand binding, activation of MAPK cascade, and phosphorylation and activation of Stat5. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 3,072 |
| Information Content | Rich |
| Other IDs | M12836 |
| Base PAG ID | WIG000315 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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